CAS No.: | 57-68-1 |
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Formula: | C12h14n4o2s |
EINECS: | 200-346-4 |
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SulfamethazineDetails
Chemical Name:Sulfamethazine
CAS No.: 57-68-1
Molecular Formula: C12H14N4O2S
Molecular Weight:278.33
Appearance:White or almost white powder
SulfamethazineTypical Properties
Item | Specifications | Results |
Identification | A:The infrared absorption spectrum; B:The chromatograms;D:The reaction of primary aromatic amines. | Meets A,B and D examine |
Melting point | About 197°C,with decomposition | 197.5-198.5°C |
Description | White or almost white powder or crystalline | Meets |
Appearance of solution | Not more than Y5,BY5 or GY5 | |
Acidity | ≤0.2ml | <0.2ml |
Related substances | Meets (≤0.5%) | Meets,<0.5% |
Heavy metals | ≤20ppm | <20ppm |
Loss on drying | ≤0.5% | 0.13% |
Sulphated ash | ≤0.1% | 0.04% |
Assay | 99.0%-101.0%(The dried substance) | 99.8% |
Conclusion | Meets BP 2012 specification |
SulfamethazineUsage
1. It is used to prevent and treat Staphylococcus and Streptococcus mutans infections, and has inhibitory effects on bacteria such as hemolytic streptococcus and pleural bacillus, mainly treating avian cholera, avian typhoid, chicken coccidiosis and the like.
2. Veterinary drugs for analysis and testing.
3. Inhibition of bacteria such as hemolytic streptococcus, pneumococcal and meningitis.
4. An antibacterial sulfa drug; induces CYP3A4 expression, and acetylation by N-acetyltransferase; exhibits a sexually dependent pharmacokinetics, produces metabolic changes through the male specific homolog CYP2C11; inhibits dihydrofolate synthesis The enzyme achieves the effect of inhibiting the synthesis of folic acid.
SulfamethazinePackaging and Shipping
Packing:Net weight 25kg/drum
SulfamethazineStorage
The warehouse is ventilated and dryat low temperatureawayfromfood